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Tumor-associated macrophages (TAMs), important immunosuppressive cells in the microenvironment, are able to activate the Gli2/IGF-2/ERK1/2 signaling axis to promote TGF- secretion and thus mediate the migration, invasion and EMT of hepatocellular carcinoma cells (Huh-7 cells) (73)

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Kodali ST, Kauffman P, Kotha SR, Yenigalla A, Veeraraghavan R, Pannu SR, Hund TJ, Satoskar AR, McDaniel JC, Maddipati RK, Parinandi NL